Largest nonprofits in Illinois by revenue
| # | Nonprofit | City | Focus area | Revenue |
|---|---|---|---|---|
| 1 | Northwestern Memorial Healthcare | Chicago | Health Care | $11.2 billion |
| 2 | Advocate Health And Hospitals Corporation | Downers Grove | Health Care | $7.8 billion |
| 3 | University Of Chicago | Chicago | Education | $5.6 billion |
| 4 | Feeding America | Chicago | Food, Agriculture & Nutrition | $5.0 billion |
| 5 | Osf Healthcare System | Peoria | Health Care | $4.4 billion |
| 6 | Northwestern University | Evanston | Recreation & Sports | $4.1 billion |
| 7 | University Of Chicago Medical Center | Chicago | Health Care | $3.6 billion |
| 8 | Northwestern Memorial Healthcare | Chicago | Health Care | $2.8 billion |
| 9 | Rush University Medical Center | Chicago | Health Care | $2.8 billion |
| 10 | Northshore University Healthsystem | Arlington Hts | Health Care | $2.3 billion |
| 11 | The Chicago Community Trust | Chicago | Philanthropy, Voluntarism & Grantmaking Foundations | $2.1 billion |
| 12 | Memorial Health System | Springfield | Not listed | $1.8 billion |
| 13 | Loyola University Medical Center | Maywood | Health Care | $1.7 billion |
| 14 | The Carle Foundation Hospital | Urbana | Health Care | $1.5 billion |
| 15 | Big Ten Conference Inc | Rosemont | Not listed | $1.5 billion |
| 16 | Advocate North Side Health Network | Downers Grove | Health Care | $1.4 billion |
| 17 | Loyola University Of Chicago | Chicago | Education | $1.1 billion |
| 18 | Depaul University | Chicago | Education | $966.9 million |
| 19 | Swedishamerican Hospital | Rockford | Health Care | $966.8 million |
| 20 | Edward Hospital | Arlington Hts | Health Care | $908.3 million |
| 21 | Sarah Bush Lincoln Health Center | Mattoon | Health Care | $841.5 million |
| 22 | St Vincent Hospital Of The Hospital Sisters Of The Third Order Of St | Springfield | Health Care | $767.1 million |
| 23 | Southern Illinois Hospital Services | Carbondale | Health Care | $765.6 million |
| 24 | Blessing Hospital | Quincy | Health Care | $731.2 million |
| 25 | St Johns Hospital Of The Hospital Sisters Of The Third Order Of St F | Springfield | Health Care | $699.1 million |
The full list includes all 3,843 Illinois nonprofits with $1M+ revenue, with street address, ZIP, EIN, assets, income and tax period, plus every other state.
Illinois cities with the most $1M+ nonprofits
- Chicago: 1,487
- Springfield: 107
- Rockford: 79
- Peoria: 66
- Evanston: 66
- Wheaton: 53
- Naperville: 42
- Schaumburg: 42
- Arlington Hts: 35
- Urbana: 35
Most common focus areas
- Human Services: 617
- Education: 493
- Health Care: 341
- Arts, Culture & Humanities: 201
- Housing & Shelter: 183
- Philanthropy, Voluntarism & Grantmaking Foundations: 139
- Community Improvement & Capacity Building: 138
- Religion-Related: 128
Where does this data come from?
The IRS Exempt Organizations Business Master File, downloaded in October 2026. Figures are as reported on each organization's latest return on file with the IRS. Personal contact names are not included.