Largest nonprofits in Pennsylvania by revenue
| # | Nonprofit | City | Focus area | Revenue |
|---|---|---|---|---|
| 1 | Upmc | Pittsburgh | Not listed | $30.3 billion |
| 2 | National Philanthropic Tr | Jenkintown | Philanthropy, Voluntarism & Grantmaking Foundations | $17.8 billion |
| 3 | Trustees Of The University Of Pennsylvania | Philadelphia | Education | $11.7 billion |
| 4 | Vanguard Charitable Endowment Program | Malvern | Philanthropy, Voluntarism & Grantmaking Foundations | $6.7 billion |
| 5 | Highmark Health | Pittsburgh | Not listed | $6.1 billion |
| 6 | Lehigh Valley Hospital | Allentown | Health Care | $4.3 billion |
| 7 | The Childrens Hospital Of Philadelphia | Philadelphia | Health Care | $4.2 billion |
| 8 | University Of Pittsburgh | Pittsburgh | Education | $3.6 billion |
| 9 | Miltons S Hershey Medical Center | Hershey | Health Care | $3.0 billion |
| 10 | Thomas Jefferson University Hospital | Philadelphia | Health Care | $3.0 billion |
| 11 | Temple University Hospital Inc | Philadelphia | Health Care | $2.7 billion |
| 12 | Carnegie Mellon University | Pittsburgh | Not listed | $2.5 billion |
| 13 | Geisinger Medical Center | Danville | Health Care | $2.0 billion |
| 14 | York Hospital | York | Health Care | $2.0 billion |
| 15 | Geisinger Clinic | Danville | Health Care | $1.9 billion |
| 16 | Main Line Hospitals Inc | Radnor | Health Care | $1.9 billion |
| 17 | Lancaster General Hospital | Lancaster | Health Care | $1.8 billion |
| 18 | St Lukes Hospital | Bethlehem | Health Care | $1.8 billion |
| 19 | Temple University-Of The Commonwealth System Of Higher Educ | Philadelphia | Education | $1.8 billion |
| 20 | Reading Hospital | West Reading | Health Care | $1.6 billion |
| 21 | Thomas Jefferson University | Philadelphia | Education | $1.6 billion |
| 22 | Drexel University | Philadelphia | Education | $1.5 billion |
| 23 | Jefferson Health Corporation | Philadelphia | Not listed | $1.4 billion |
| 24 | Presbyterian Medical Center Of The University Of Pennsylvania Health | Philadelphia | Health Care | $1.4 billion |
| 25 | Community Behavorial Health | Philadelphia | Mental Health & Crisis Intervention | $1.3 billion |
The full list includes all 4,951 Pennsylvania nonprofits with $1M+ revenue, with street address, ZIP, EIN, assets, income and tax period, plus every other state.
Pennsylvania cities with the most $1M+ nonprofits
- Philadelphia: 944
- Pittsburgh: 586
- Harrisburg: 115
- Lancaster: 111
- Erie: 105
- Allentown: 95
- York: 79
- Bethlehem: 60
- Reading: 53
- Scranton: 53
Most common focus areas
- Human Services: 796
- Education: 771
- Health Care: 613
- Arts, Culture & Humanities: 264
- Housing & Shelter: 200
- Mental Health & Crisis Intervention: 196
- Community Improvement & Capacity Building: 189
- Philanthropy, Voluntarism & Grantmaking Foundations: 171
Where does this data come from?
The IRS Exempt Organizations Business Master File, downloaded in October 2026. Figures are as reported on each organization's latest return on file with the IRS. Personal contact names are not included.